Western New York Immediate Care is now AFC Urgent Care. Same 3 locations. Walk-ins welcome.
AFC Urgent Care AFC Urgent Care
Walk-Ins Welcome
Areas we serve: Buffalo Depew Orchard Park All
AFC Urgent Care · Formerly WNY Immediate Care

Urgent Care in Depew, NY

Trusted Walk-In Urgent Care Serving Depew, New York

Illness and injury rarely wait for a convenient time, and neither should you. AFC Urgent Care is located at 6375 Transit Rd in Depew (14043), giving patients across Western New York a fast, reliable alternative to overcrowded ERs and backed-up doctor schedules. Our clinic is easy to reach from Lancaster (14086), Cheektowaga (14225 / 14227), Sloan (14227), Williamsville (14221), Clarence (14032), Clarence Center (14031), West Seneca's northern neighborhoods (14224), Bowmansville (14026), and Alden (14004). If you've been typing "urgent care near me" in Depew, this is the clinic that keeps popping up for a reason.

No appointment needed Open 7 days On-site X-rays
Save Your Spot Call 716-684-2273

Depew-Area Towns and ZIP Codes We Serve

Families from Alden to Williamsville choose our Depew clinic at Lancaster-Tops Plaza for dependable, all-ages urgent care.

Why Depew and the Surrounding Area Trust AFC Urgent Care

American Family Care was founded on a simple promise: patients deserve fast, high-quality medical treatment without the runaround. That philosophy shapes everything happening inside our Transit Rd location. Our providers are trained to evaluate, diagnose, and treat a wide range of non-life-threatening conditions in a single visit, so families in Depew and neighboring towns aren't left waiting on referrals or callback windows that stretch into next week. We treat every patient who walks through our door as an individual, not a number on a schedule. That means real face time with a provider, whether you're coming in for a torn ligament after a weekend game or bringing in a toddler running a fever at 6 p.m. on a Tuesday. Most major insurance plans are accepted, and for patients paying out of pocket, our pricing is upfront and reasonable from the start. For households comparing walk-in clinics across Depew, Lancaster, and Cheektowaga, we intend to make that decision an easy one.

Services and Conditions We Treat On-Site

Our Depew clinic is fully equipped to handle the everyday medical issues that send people searching for a walk-in clinic instead of an appointment three weeks out. Patients regularly come to us for:

  • Cuts, minor fractures, sprains and burns
  • Flu, strep throat, colds and other seasonal illnesses
  • STI and STD testing
  • Sports, school and DOT physicals
  • Travel vaccinations and pre-trip medical consultations
  • Occupational health services and workplace injury treatment
  • Routine immunizations
  • On-site digital X-rays for same-visit diagnosis
See all services at our 3 clinics →

A Clinic Built Around Real Schedules

Our Depew team understands that a Lancaster parent juggling school pickup, a Cheektowaga shift worker squeezing in a physical between jobs, and a Clarence retiree managing a minor injury all need the same thing: care that fits into their day, not the other way around. That's why our process is built to get patients from check-in to treatment quickly, no matter what brought them in.

Walk In Anytime, or Reserve Your Spot Online

There's no need to call ahead or wait for an opening. AFC Urgent Care in Depew welcomes walk-ins every day of the week, and patients who'd rather plan around their day can reserve a time slot online before arriving. With extended weekday hours and weekend availability, care is there when you actually need it, not just during a narrow weekday window.

Patients from across zip codes 14004, 14026, 14031, 14032, 14043, 14086, 14221, 14224, 14225, and 14227 choose our Depew location for the same reason: dependable, all-ages urgent care that's ready the moment you walk in.

Visit AFC Urgent Care at 6375 Transit Rd in Depew, NY, the next time you need a walk-in clinic near you.

Save Your Spot Call 716-684-2273

FAQs: Urgent Care in Depew, NY

Where is the closest urgent care near me in Depew?

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AFC Urgent Care is located at 6375 Transit Rd in Depew, NY 14043, just minutes from Lancaster, Cheektowaga, and Sloan.

Do I need an appointment to be seen at AFC Urgent Care in Depew?

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No appointment is required. We accept walk-ins seven days a week, and online scheduling is available for patients who want to reserve a specific arrival time.

Does the Depew AFC Urgent Care location have on-site X-rays?

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Yes. Our Transit Rd clinic offers on-site digital X-rays along with lab testing, physicals, and treatment for common illnesses and injuries, all in one visit.

What towns and zip codes does AFC Urgent Care in Depew serve?

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We regularly see patients from Depew, Lancaster, Cheektowaga, Sloan, Williamsville, Clarence, Clarence Center, northern West Seneca, Bowmansville, and Alden, covering zip codes 14004, 14026, 14031, 14032, 14043, 14086, 14221, 14224, 14225, and 14227.

What are the hours for AFC Urgent Care in Depew, NY?

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We're open seven days a week with extended weekday hours, so you can get treated in the evening or on a weekend without a trip to the emergency room.

More areas served by AFC Depew

Other AFC Urgent Care Clinics Nearby

Urgent Care in Buffalo, NY 2228 Delaware Avenue, Suite 200, Buffalo, NY 14216 · 716-874-2273 Serving Kenmore · Tonawanda · Amherst · Grand Island Urgent Care in Orchard Park, NY 3346 Southwestern Boulevard, Orchard Park, NY 14127 · 716-675-3700 Serving Hamburg · West Seneca · Lackawanna · East Aurora